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Home » News » A dramatic rethink of Parkinson’s offers new hope for treatment
Science

A dramatic rethink of Parkinson’s offers new hope for treatment

Daniel PetersonBy Daniel Peterson Science
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New scientist. Science News and Long Reads of expert journalists, who cover developments in science, technology, health and environment on the website and the magazine.

According to the moment “Aha” of Borghammer arrived almost 20 years ago. The neuroscientist was reading a document of researchers who examined ReM sleep behavior disorder (RBD), a condition that causes people to act their dreams are often in people who then develop the rest, it could be.

Instead of starting with the brain, in principle, the equipment sought the loss of nerve cells in the heart. Although Parkinson’s is historical associated with the exhaustion of nerve cells in the brain, it also affects neurons in the heart that handle autonomous functions such as heart rate and blood pressure. And, says Borghammer, “in all these patients, the heart is invisible; it has gone.”

Not literally, no course. But in these people, the neurons that produce the norepinephrine neurotransmitter, which helps control the heart rate, were so exhausted that their hearts did not appear in scans using radioactive tracers. This type of neuron loss is associated with that of Parkinson’s, but at that time, none of the people had diagnosed the leg with the disease and their brain scans seemed normal.

What Borghammer hit was that Parkinson did not seem to follow the same trajectory in all that affected: RBD strongly predicts that of Parkinson’s, but not all with Parkinson RBD’s experiences.

“I realized that Parkinson must be at least two types,” says Borghammer: when the loss of neurons begins the brain, Angelly makes its way and when the loss of neurons is largely limited to the brain from the beginning. For 2019, Borghammer, …

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